Alex Arthur will make the first defence of his WBO super-featherweight title against Nicky Cook on September 6 at the MEN Arena.
The thirty-year Scotsman was upgraded from interim champion after Juan Guzman pulled out of a May defence.
A former British, Commonwealth and European champion at featherweight, Cook is rated in the WBO top 10 at super-feather.
The 28-year-old, who is trained by his father Paul has a 28-1 record, his only defeat coming last July when he challenged Steven Lueavno for the vacant WBO featherweight title. Since then he has moved up a division.
Arthur told FrankWarren.tv this morning: "This is a great fight for Britain and will follow in a long line of classic domestic fights.
"I jumped at the chance when I was told it would be Cook, and it's given my training an added edge.
"I know he will come into the ring trying to rip my title away from me, but I'm confident I will walk away from Manchester as the WBO champion."
Amir Khan will defend his Commonwealth lightweight title on the card.